MICROCOCCUS LANCEOLATUS. 515 



In all there was a decided fall of temperature in from 

 six to twelve hours after subcutaneous injections of from 

 4 to 6 c.c. of the serum. The pulse and respirations 

 were also diminished in frequency. In two cases the 

 temperature fell to 37 C. Twice it fell and remained 

 at normal. In other cases it fell only temporarily. 



The number of cases reported in which the blood- 

 serum of animals artificially immunized against pneu- 

 monic infection has been used for the treatment of the 

 disease, although considerable, is still too few to warrant 

 the expression of any definite opinion as to the final 

 value of this as a therapeutic agent. In the cases we 

 have observed there has been in some a slight imme- 

 diate lowering of the temperature ; in others no ap- 

 parent change. As a rule, the cases did rather better 

 than was expected, but certainly no striking curative 

 effects were apparent. The cases did not develop 

 pnetimococcus blood infection, and it seems probable 

 that the serum may be able to prevent a general infec- 

 tion from taking place from the diseased lung, even 

 though it may fail to influence the local process. It 

 has also been shown that these injections of antipneu- 

 motoxic serum are practically harmless. 



