THE FUNGI. 619 



tion of the fungus are found to have disappeared, leav- 

 ing only the remains of the club-like ends, thus showing 

 that no growth has taken place. Ponfick, Johne, Rot- 

 ter, Liming, and Hanan claim to have obtained positive 

 results in animals, but according to Bostrom these re- 

 sults are not conclusive. The animals used for experi- 

 mentation have been calves, swine, dogs, rabbits, and 

 guinea-pigs, the places of inoculation being the anterior 

 chamber of the eye, the subcutaneous intercellular tissue, 

 the peritoneum, and the blood; and the material em- 

 ployed for inoculation, pus from the infected regions in 

 animals and man; very rarely cultures. 



A number of other streptothrices have been described 

 in connection with pathogenic processes, but most of 

 them are not well defined. They have been found in 

 brain abscess, cerebro-spinal meningitis, pneumonic 

 areas, and in other pathological conditions. Eppinger 

 injected cultures into guinea-pigs and rabbits, and ob- 

 served that it caused a typical pseudotuberculosis. Con- 

 solidation of portions of both lungs, thickening of the 

 peritoneum, and scattered nodules resembling tubercles, 

 were noted in a case of human infection as due to a 

 streptothrix by Flexner, in which the pathological 

 picture of the disease resembled so nearly tuberculosis 

 in human beings that the two diseases could be sepa- 

 rated only by the causative micro organism in each case. 



THE FUNGI. 



Most of the fungi are not pathogenic and interest us 

 merely as organisms which are apt to infect our bac- 

 teriological media. Some are, however, true parasites, 

 and already we know that ringworm, favus, thrush, and 

 pityriasis versicolor are caused by fungi. Only those 

 causing ringworm and favus can be touched on here. 



