264 



ACTINOMYCOSIS. 



form a dense fringe around the colony, and when stained 

 by Gram's method retain the violet stain. They have, in 

 fact, undergone some further chemical change which pro- 

 duces the altered staining reaction. Clubs showing inter- 

 mediate staining reaction have been described by M'Fadyean. 

 The view that the clubs are organs of fructification has been 



FIG. 67. Actinomyces in human kidney, showing clubs radially 

 arranged and surrounded by pus. The filaments had practically dis- 

 appeared. 



Paraffin section ; stained with hasmatoxylin and rubin. x 500. 



abandoned by most authorities, and there appears to us 

 little evidence in support of it. 



Structural Arrangement of the Colonies. The arrange- 

 ment in the human subject differs somewhat from that in 

 the ox, the difference being chiefly due to the fact that in 

 the latter the disease is more chronic, and most of the 



