402 CHOLERA. 



oedema, and a rapidly fatal septicaemia. Young fowls 

 can be infected by feeding with virulent cultures, and 

 guinea-pigs, too, sometimes contract a similar disease without 

 any special preparation, e.g., by neutralising the gastric 

 contents, etc. We have evidence from the work of Gamaleia 

 that the toxines of this organism have somewhat the same 

 action as those of the cholera organism. 



The organism is therefore one which very closely 

 resembles the cholera organism, the difference in the 



effect on inoculat- 

 ing the pigeon offer- 

 ing the most ready 

 i O *~ means of distinction. 



V $fr s vU ^ ^ &* ves a ne a tive 



reaction to Pfeiffer's 



iViV-t\ ' '<< ,)' test; that is ' the 

 properties of an and- j 



cholera serum are not 

 exerted against it. It 

 may also be men- 

 tioned that an or- 

 ganism which is ap- 



S ^A*, parently the same as 



the vibrio Metchni-j 



FIG. 97. Finkler and Prior's spirillum, koviwas cultivated by 

 gr wth n ^ CUUUre f twenty ' f ur h urs> Pfuhl from water, and 



Stained with carbol-fuchsin. x 1000. named v. Nordhafen. j 



Finkler and 



Prior's Spirillum. These observers, shortly after Koch's] 

 discovery of the cholera organism, separated a spirillum, 1 

 in a case of cholera nostras, from the stools after they 

 had been allowed to decompose for several days.] 

 Morphologically this organism closely resembles Koch's \ 

 spirillum, and cannot be distinguished from it by its 

 microscopical characters, although, on the whole, it tends 

 to be rather thicker in the centre and more pointed at the 

 ends (Fig. 97). In cultures, however, it presents marked 

 differences. In puncture cultures on gelatine it grows 



