MICROCOCCUS IXTRACELLULARIS. 303 



Fifth, when obtained in pure culture by either of the 

 special procedures noted above, its cultivation may be 

 continued upon the same medium ; but growth will 

 usually not be observed if it is transplanted to ordi- 

 nary nutrient gelatin, agar-agar, bouillon, or potato ; 

 should it grow under these circumstances its develop- 

 ment will be very feeble. (Is this the case with com- 

 mon pus-producers ?) 



Sixth, it has no pathogenic properties for animals, 

 while several of the pyogenic cocci, notably micrococcus 

 aureus and streptococcus pyogencs, are usually capable 

 of exciting pathological conditions. (This is less com- 

 monly true of streptococcus pyogenes than of micrococcus 

 aureus.) 



MICKOCOCCUS INTRACELLULARIS (WEICHSELBUAM), 

 MIGULA, 1900. 



Synonyms : Diplococcus intracellularis meningitidis, Weichselbaum, 

 1887; Streptococcus intracellularis (Weichselbaum), Lehmanu and 

 Neumann, 1896. 



Of the several organisms mentioned that might be 

 mistaken for the gonococcus, no one of them is as sug- 

 gestive and none, per se, so important as that concerned 

 in the causation of epidemic cerebrospinal meningitis. 



This organism, described by Weichselbaum in 1887 

 under the name "diplococcus intracellularis meningi- 

 tidis," was found by him in the exudations of the brain and 

 spinal cord in six cases of acute cerebrospinal meningitis. 



As its name implies, it is a diplococcus, practically 

 always seen within the bodies of pus-cells (polymorpho- 

 nuclear leucocytes) in the exudations characteristic of 

 this disease. It is not seen within the other cells of the 

 morbid process. It stains readily with any of the ordi- 



