PSEUDOMONAS ^RLfGINOSA. 315 



may not ensue, and only a local inflammatory reaction 

 (abscess-formation) may be set up. In these cases the 

 animals are usually protected against subsequent inocu- 

 lation with doses that would otherwise prove fatal. 



Most interesting in connection with pseudomonas 

 ceruginosa is the fact, as brought out in the experiments 

 of Bouchard, and of Charrin and others, that its prod- 

 ucts possess the power of counteracting the pathogenic 

 activities of bacterium anthracis. That is to say, if an 

 animal be inoculated with a virulent anthrax culture, 

 and soon after be inoculated with a culture of pseudo- 

 monas ceruginosa, the fatal effects of the former inocu- 

 lation may be prevented. Emmerich and Low ' are 

 inclined to attribute this to the direct bacteriolytic action 

 of the enzymes upon the anthrax bacteria introduced 

 into the tissues. 



In the literature upon the green-producing organisms 

 that have been found in inflammatory conditions sev- 

 eral varieties believed to be distinct species have 

 been described ; but when cultivated side by side their 

 biological differences are seen to be so slight as to ren- 

 der it probable that they are but modifications of one 

 and the same species. 



BACILLUS PESTIS, YERSIN, 1 894. 

 THE BACILLUS OF BUBONIC PLAGUE. 



Before passing from the subject of suppuration it 

 may not be inappropriate to call attention to the light 

 that modern methods of investigation have shed upon 

 the etiology of bubonic plague, an epidemic disease 



1 Miinchener med. Wochenschrift, 1898, No. 40 ; Centralblatt fiir 

 Bakteriologie uncl Parasitenkunde, 1899, Abt. i. No. 1, p. 33. 



