V1 PREFACE. 



'Another feature wi^ich I have desired to render pro- 

 minent in this work is the description of the methods 

 which have been followed m important and, to borrow a 

 convenient Germanism, ' epocli - making ' researches. It 

 seemed the more important to do this as I desired to write 

 in the interest of the truly scientific student, anxious not 

 merely to learn what has been already Acquired to science, 

 but wishful himself to extend her boundaries.' 



1 1 have, as far as possible, tried all the experimental 

 processes mentioned in this book, and throughout it I have 

 incorporated the results of my own independent!-, researches 

 which, in many cases, have not yet been published else- 

 where.' 



The publication of several excellent Manuals, such as 

 those of Hammarsten and of Haliburton, which deal, in a 

 comprehensive but necessarily succinct manner, with the 

 whole field of Physiological Chemistry, have adequately 

 met the wants of a large class of students whilst, I venture 

 to think, they have left the field open for a work which 

 shall be based on an original study of the whole literati ire 

 of the subjects treated of, and which shall be an accurate* 

 guide to the advanced student and the original worker, 

 both in the study and the laboratory. 



As in the first volume, though in a more detailed 

 manner, I have written not merely as a scientific chemist, 

 but from the stand-point of the physiologist, and I have 

 treated with especial care all subjects which are of interest 

 to the pathologist, the pharmacologist, and the scientific 

 physician. 



In illustration, I may cite the chapters in which I 

 discuss the pathology of jaundice, the pharmacology of 

 icterogenic poisonous agents and of cholagogues, the struc- 



