116 RESEARCHES OF BRUCKE AND SCHUTZENBERGER, [BOOK II. 



which we term albumoses, whilst peptone 7 corresponds to peptone 

 properly so-called. 



On the prolonged digestion of casein or of fibrin, 



Meissner obtained a certain flocculent insoluble residue, 



to which he gave the name of dyspeptone. This body was insoluble 



in 0'2 per cent. HCL, but soluble in stronger acids. It consisted of a 



mixture of antialbumid (see p. 121) with nucleins. 



Bruckes views on the Digestion of Proteids. 



According to Briicke, when a typical proteid unboiled fibrin is 

 subjected to peptic digestion, the following steps in the process occur. 

 The fibrin is dissolved and, in great part, converted into acid-albumin 

 or parapeptone, though even from the first some peptone is produced. 

 At this stage a large precipitate is obtained on neutralising the liquid 

 (Meissner 's parapeptone). If digestion be very long continued, how- 

 ever (sometimes days are needed), the parapeptone disappears, so 

 that no precipitate is obtained on neutralising 1 , and the solution 

 merely contains peptones. 



The bodies taken for parapeptones by Brticke were, doubtless, in 

 great part albumoses. 



The Researches of Schutzenberger 2 . 

 Hemiprotein and Hemialbumin. 



In the year 1885 Schutzenberger published the results of a series 

 of important researches on the products of decomposition obtained 

 when albuminous substances are (a) subjected to long-continued 

 boiling with dilute sulphuric acid, (b) digested in closed vessels at 

 temperatures varying between 100C. and 150C. with solution of 

 barium hydrate. 



Under the Schutzenberger placed a kilogramme of moist 

 influence of coagulated albumin, in 6-8 litres of water, to which 

 boiling dilute 200 grams of H 2 SO 4 has been added, and boiled this 

 e 1 P ui" m ^ x ^ ure between one-and-a-half and two hours. On 

 is split up into allowing the mixture to cool, there separated a floe- 

 two moieties, culent, homogeneous precipitate, resembling silica, or 

 Hemiprotein freshly precipitated magnesia. The latter, collected 

 i Hemiaibu- on a }^ erj washed, and dried, presented the appearance 

 of yellowish transparent masses, which yielded a nearly 



1 In the nitrate from the precipitate there is, besides peptone, a soluble proteid 

 which is coagulable on boiling. 



2 M. P. Schutzenberger, 'Recherches sur I'albumme et les matieres albuminoides/ 

 Bulletin de la Societe Chimique de Paris. Tomes (23) pp. 161, 193, 216, 242, 385, 433, 

 (24) pp. 2 et 145. 



These papers are abstracted at great length and with much ability in Maly'i 

 Jahresbericht, Bd. v. (1875), pp. 209 313. 





