CHAP. II.] THE RESEARCHES OF SCHUTZENBERGER. 117 



white, not hygroscopic powder, insoluble in water, alcohol and ether. 

 This substance was found by Schiitzenberger to amount approxi- 

 mately to one-half the weight Vf the albumin operated upon. To 

 it he gave the name Hemiprotein. He found it to be amorphous, 

 soluble in alkalies, from its solutions in which it could be precipitated 

 on neutralising with acids, the precipitate being dissolved by an excess 

 of acid. 



The following are the results of elementary analyses of Hemi- 

 protein, dried at 110 C. 



(1) (2) (3) (4) (5) (6) (7) (8) 

 C. 52-66 54-83 53'33 ............... 



H. 7-01 7-25 7'31 ............... 



N .......... 14-27 14-46 15'08 14*26 14*22 



Hemiprotein contains sulphur, the amount of which has not been 

 determined. 



Hemipro- Schiitzenberger found that when hemiprotein was 



further subjected to a process of long boiling with 

 dilute sulphuric acid, it furnished leucin and tyrosin, and as a chief 

 product, an amorphous substance of a feebly sweet taste, soluble in 

 water and alcohol, to which he gave the name of Hemiproteidin, to 

 which as a result of his analyses, he assigned the empirical formula 



Hemiaibumin. Returning now to the original operation which 

 yielded the insoluble hemiprotein, Schiitzenberger found 

 that the acid filtrate from the latter contained, as its principal con- 

 stituent, an amorphous substance, of feebly acid reaction, and con- 

 taining approximately C 50/o, H 7% N 15*4/ , to which he gave the 

 name Hemiaibumin, and the formula C 24 H 40 N 6 10 . 



In addition to the two principal products of the decomposition of 

 the proteid molecule by boiling dilute sulphuric acid, Schiitzenberger 

 obtained evidence of the presence of many other interesting by- 

 products, as for instance, a substance similar to, if not identical with, 

 sarcine, a non-nitrogenous, strongly reducing, body apparently re- 

 sembling glucose, and a dibasic acid, represented by the empirical 

 formula C 24 H 40 N 6 O 15 . 



Kuhnes Observations and Theoretical Views. 



Whilst Schiitzenberger was devoting his attention to the in- 

 vestigations some of the results of which have been referred to, 

 Kuhne had been studying the profound decomposition which the 

 proteid molecule undergoes under the influence of trypsin, as he 

 termed the powerful proteolytic enzyme of the pancreas and its 

 secretion. 



