CHAP. It.] 



THE BLOOD. 



61 



in which he determined the total quantity of proteids in the serum 

 and also the amount of serum-globulin; the quantity of serum-albumin 

 being found by subtracting the second result from the first. It will 

 be seen that according to Hammarsten the proportion of serum- 

 globulin to serum-albumin varies remarkably, in some cases (horse and 

 ox) the former being the more abundant constituent, in others (dog 

 and rabbit) the latter. 



TABLE SHEWING THE AMOUNT OF SOLIDS, PROTEIDS, AND ALSO THE 

 RELATIVE PROPORTIONS OF SERUM-GLOBULIN AND SERUM-ALBU- 

 MIN IN 100 PARTS OF THE SERUM OBTAINED FROM THE BLOOD 

 OF VARIOUS ANIMALS 1 . 



By the term serum-casein some authors have designated the proteid 

 matter which is obtained from serum by adding a small quantity of acetic 

 acid to it after paraglobulin lias been precipitated by diluting and subjecting 

 to a stream of C0 2 . We now know, however, that dilution with water and 

 the action of CO 2 are not sufficient to precipitate all the serum-globulin 

 contained in the serum, and we cannot doubt that Panum's serum-casein 

 is merely serum-globulin which has escaped precipitation by CO 2 . 3 



2. Serum-albumin. 



Having separated from the serum the serum-globulin which 

 it contains, there still remains in solution the most important and 

 usually the most abundant of its constituents, viz. serum-albumin. 



In consequence of the serum-albumin which it contains, when 

 serum is heated to about 60 C. it becomes slightly opaque, full 

 coagulation occurring at 75, the separation of the albumin being 

 accompanied by an increase in the alkaline reaction of the liquid. 



1 Hammarsten, "Ueber das Paraglobulin." PMger's Archiv, 1878. 



2 The reader who wishes to acquaint himself with the older statements as to serum - 

 casein is referred to Kiihne, Lehrbuch, p. 175, .and to .Gorup-Besanez, Lehrbuch d. 

 pkysiolog. Chemie, 1878, p. 119. 



