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intake. Lakso and Peoples (1975) noted both trivalent and 

 pentavalent forms of arsenic were methylated in the body and 

 largely excreted via the urine. Urinary excretion in cattle is 

 rapid with 54 to 98 percent of the daily intake eliminated in the 

 urine (Peoples 1964). Normal urine arsenic levels for cattle and 

 horses are reported as 0.5 and 0.4 ppm, respectively (Puis 1981) . 

 Lakso and Peoples (1975) found a range of 0.17 to 0.31 ppm arsenic 

 in urine of control cattle that they tested. Selby and Dorn (1974) 

 found 1400 ug/100 ml of arsenic in the urine of acutely poisoned 

 steers. Puis (1981) noted urine levels of 2 to 14 ppm and 100 to 

 150 ppm as indicative of acute toxicosis in cattle and sheep, 

 respectively. 



Background arsenic concentrations in cattle blood have been 

 reported as 0.03 to 0.07 ppm (Edwards and Clay 1979). Blood 

 arsenic levels may be more insensitive to intake at low levels 

 than are arsenic levels in urine. Peoples (1964) found no change 

 in arsenic blood levels among cattle fed 0.0 to 1.25 mg/kg body 

 weight arsenic acid. Shar iatpanahi and Anderson (1984a, 1984b) 

 found blood arsenic levels increased rapidly following ingestion 

 of monosodium methanear sonate in sheep and goats. A near steady 

 state approximately 3 orders of magnitude above background levels 

 was observed within 10 days under daily ingestion of 10 mg/kg body 

 weight of arsenic. These authors also reported a rapid decline in 

 blood arsenic levels following removal of arsenic from the diet. 

 Edwards and Clay (1979) found low concentrations of arsenic (0.03 

 to 0.12 ppm) in the blood of cattle exposed to toxic concentra- 

 tions of arsenic in contaminated forage one year prior to sam- 

 pling. The concentration range was not significantly different 

 from non-exposed cattle. Puis (1981) has given normal blood 

 arsenic levels as 0.05 and 0.01 ppm for cattle and swine,, respec- 

 tively. High blood levels for sheep were reported as 0.04 to 0.08 

 ppm and toxic levels were given as 0.17 to 1.0 and 5.0 ppm for 

 cattle and sheep, respectively (Puis 1981). 



Levels of arsenic in normal milk have been reported to range 

 from 0.0005 to 0.17 ppm (NRC 1977, Iyengar 1982). Peoples (1964) 

 found nc significant correlation between arsenic in milk and 



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