0141658 



values for zinc in whole blood are apparently slightly higher than 

 respective values for serum. The background range for zinc in 

 whole blood is 1.02 to 3.74 ppm (Miller et al . 1968, Bertrand et 

 al. 1981). 



The background range for zinc in .cattle kidney tissue 

 reported by Flanjak and Lee (1979) (12.9 to 31.6 ppm) encompasses 

 all other background values found in the literature. The highest 

 reported nontoxic value for this parameter was 76 ppm (Ott et al. 

 1966d). The toxic hazard level suggested for zinc concentrations 

 in cattle kidney tissue is 130 to 140 ppm. This range is based on 

 the 130 ppm level reported to be toxic by Puis (1981) and the 140 

 ppm found to be toxic by Allen et al. (1983). 



Flanjak and Lee (1979) reported the maximum background range 

 (13.4 to 99.2 ppm) of zinc in cattle liver tissue and Ott et al . 

 (1966d) noted that 86 and 159 ppm in calf liver tissue were 

 nontoxic but also noted that 136 ppm was toxic. The 86 ppm 

 tolerable level for this parameter is thus based on the highest 

 nontoxic value below the lowest reported toxic value. The toxic 

 hazard level of 300 ppm for cattle liver tissue is based on the 

 work of Ott et al . (1966d). These authors reported toxicity at 

 liver zinc concentrations of 136 to 326 ppm. Several authors 

 reported nontoxic liver zinc levels in the interval of 136 to 186 

 ppm. All values derived from the literature which exceeded 300 

 ppm were associated with zinc toxicity. Puis (1981) reported a 

 value of >500 ppm as the toxic concentration of zinc in cattle 

 liver tissue. 



Background values of zinc in cattle hair have been reported 

 to range from 79.2 ppm (Miller et al. 1965b) to 142 ppm (Ott et 

 al. 1966d). Zinc concentrations in cattle hair associated with 

 toxicity ranged from 154 to 173 ppm (Table 24). With one excep- 

 tion (158 ppm) , all values which exceeded the suggested 154 ppm 

 hazard level were toxic. Puis (1981) reported a range of 100 to 

 150 ppm zinc in cattle hair as high ("levels elevated well above 

 normal but not necessarily toxic"). No other data were found in 

 the reviewed literature for this oarameter. 



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