890 PHYSIOLOGY OF DIGESTION AND SECRETION. 



inhibiting hormone given off by the pancreas. When the pancreas 

 is removed, the accelerating hormone causes an augmentation in 

 the output of sugar and thus produces a condition of hypergly- 

 cemia and glycosuria. In support of this view it is claimed that in 

 a depancreatized dog ligation of the adrenal veins prevents the 

 glycosuria. Unfortunately, we can hardly accept this relatively 

 simple hypothesis as expressing the whole truth, for apparently the 

 relation of the sugar-regulating mechanism of the body to the in- 

 ternal secretions is involved and concerns a number of the ductless 

 glands. For example, the posterior lobe of the pituitary body ap- 

 pears to exert an influence on the conversion of glycogen to sugar 

 similar to that attributed to epinephrin, while, on the other hand, 

 thyroid secretion, or at least thyroid feeding, inhibits the forma- 

 tion of glycogen in the liver.* 



* Cramer and Krause, "Proceedings of the Royal Society," London, B. 86, 

 550, 1913. 



