NEOPLASTIC DISEASES IX CHICKENS 



33 



heart's blood. The histology of the tumor was portra\ed best in foci in the heart 

 and lung. The t\pe cell was the angioblast. In some areas these were compact 

 and in others they tended to form small spaces which were filled with blood. 

 The lining of the larger blood spaces was stretched thin. In many of the larger 

 blood spaces the blood was coagulated and varying degrees of organization were 

 apparent. Although no section was made of the tissue surrounding the blood 

 clot in the left foot pad it is possible that this lesion represented a focus of tumor. 



2. Case T 291. The bird was thin and inactive when killed for necropsy. The 

 liver was markedh" enlarged, with a somewhat greater relative enlargement of 

 the right lobe. Numerous areas of coagulated blood of variable size were scat- 

 tered throughout the substance of the organ. A few similar masses of clotted 

 blood were found in the anterior pole of the right kidney. Sections prepared 

 from the liver revealed a histology so altered that the tissue could scarcely be 

 recognized as liver. The bulk of the parench\ma was replaced by neoplastic 

 cells which tended to form walls enclosing masses of blood. In some areas the 

 tumor cells were in a sheetlike, s^ncitial arrangement without definite order. 

 An irregular, patchy granulocytic infiltration was evident throughout the liver. 

 Neoplastic angioblasts were found around the blood clots in the kidney. The 

 bone marrow and spleen were found negative upon histological examination. 



3. Case T 46. A tumor mass was found in a bird which the owner had killed 

 and dressed for food. The carcass was in good flesh and the bird had shown no 

 symptoms of disease. The tumor mass, which measured 35 X 25 X 20 mm. 

 and weighed 150 grams, was found attached to the ovary. The ovarian tissue 

 itself was inactive and appeared normal. The tumor was dark red with irregular 

 yellow areas. The colors were obviously due to coagulated masses of blood in 

 v^arious stages of organization. Upon section, the masses of blood were found 

 surrounded b\' a membrane formed of a thin, stretched angioblast type of cell. 

 Between the large masses of blood, the tunTor cells tended to form small capil- 

 laries, some of which did not contain blood in the lumen. Histological section 

 of the normal-appearing part of the ovar\- revealed no pathology. 



4. Case T 98. A bird with a respiratory infection was killed for examination. 

 An incidental finding was a small (2 mm. in diameter), gra\' nodule beneath the 

 capsule of the left lobe of the liver. This nodule was made up of imperfectly 

 formed capillaries, a few of which contained blood cells in their lumens. Inter- 

 spersed between the vessels were many granulocytes. 



5. Case T 280. The bird providing material for this case was affected with 

 histiocytic sarcoma and is described in the section dealing with that form of 

 neoplasia. The histiocytic sarcoma was confined to the subcutis of the pectoral 

 region and both lungs. A small gray mass was noted beneath the capsule of the 

 liver. On section, this proved to be an area composed of angioblasts forming 

 fairly well developed capillaries (Plate XI, Figure 2). 



Three of the five cases of hemangioma described may be considered as the 

 cavernous form and the other two as the capillary form (Table 16). Only two 

 of the cases (Cases 444 and T 291) were malignant as indicated by extent of the 

 tumor growth. Both of the cases regarded as malignant were of the cavernous 

 form, and in these birds the lesions were responsible for serious illness. The small 



Table 16. — Dat.\ on Five Cases of HEMANG:ci:A. 



Case 



No. 



Age 

 (Weeks) 



Location of Tunic 



Form of Tumor 



444 *D 22 Female Li\er, kidne\s, lungs, heart, spleen Cavernous 



T 291 K 28 Female Liver, kidney Cavernous 



T 46 K 52 Female Ovar)- Cavernous 



T 98 K 32 Female Liver Capillary 



T 280 K 28 Female Liver Capillary 



*D indicates that bird died; K, that it was killed for examination. 



