NEOPLASTIC DISEASES IN CHICKENS 



41 



Table 18. — Data on Egg Production of Chickens with Carcinosarcoma. 



Productive life is the interval between first and last eggs laid. 

 Production index is the factor obtained by dividing the number of eggs laid 

 by the productive life in days. 



*K indicates that bird was killed for examination; D, that it died. 

 **Also leiomyoma in mesosalpinx. 



and must be regarded as the primary site of origin; the same applies for the 

 pancreas in two cases and the adrenal in one. In the remaining case both the 

 ovary and pancreas were involved. An interesting and complicating factor 

 was the finding of a leiomyoma of the mesosalpinx in four of the cases. For con- 

 venience the distribution of lesions is arranged in tabular form (Table 19). 



Table 19. — Distribution in Seven Cases of Carcinosarcom.\. 



Organ or Tissues -Effected 

 Adrenal 



Mixed 



♦Smooth muscle cells intermingled with connective tissue in substance of tumor. 

 **Tumor composed of a mixture of epithelial and connective tissue. 



Jackson (13) has given an excellent description and discussion of a type of 

 disease which he terms "carcinoma leiomyomatosum." Four such cases were 

 found in the collecti.Jn which he studied. One of Jackson's cases is of particular 

 significance with respect to the pathogenesis of mixed tumors. In this case the 

 adenomatous tumor was believed to have originated in the wall of the oviduct, 

 spread by direct extension to the serous surfaces of the visceral organs, and 

 invaded the substance of the ovary and pancreas. In these locations there was an 

 abundance of neaplastic-like smooth muscle tissue suppK ing the stroma for the 

 epithelial elements. Tumor foci were also found in the liver, but they were com- 

 posed only of epithelial elements. On the basis of this case Jackson came to the 



