H. B. van Dyke 



15 



iodine has been split from colloid iodine; for the hyperplastic 

 thyroid glands present exhibit no significant change in iodine con- 

 tent and yet are able quickly to bind any iodine available as iodide. 

 In the experiments reported in Table III colloid iodine solution 

 of animals with hyperplastic glands, each of which had received an 



TABLE II. 



Ratio of the Percentage of Iodine in Cells to the Percentage of Iodine in 

 Whole Gland in Hyperplastic Thyroid Glands of Dogs after the Intrav- 

 enous Injection of Thyroid Colloid Iodine from Normal Dog 

 Thyroid Glands. The Iodine Content of a Hyperplastic 

 Gland of a Dog after the Injection of a Comparable 

 Amount of Inorganic Iodine is also Recorded. 



intravenous injection of 50 mg. of KI 60 minutes before the removal 

 of the thyroid lobe for section, was injected intravenously as soon 

 as possible into other animals with hyperplastic glands. The 

 sequence was as follows: as a control, part of one lobe was removed; 

 colloid iodine dissolved in Ringer's solution was then injected and 

 all but half of one lobe resected; a comparable amount of iodine 

 as KI dissolved in a similar amount of Ringer's solution was then 



