138 CONTAGIOUS DISEASES OF DOMESTICATED ANIMALS. 



muuitj it is advised to make more careful selection of the virus from 

 a lung enjjor.ii'ed yellow and already slightly fibrinous, or from tlie snb- 

 cutaneous connective tissue in an inoculated region rich in that tissue, to 

 repeat the operation after a certain lapse of time, as advised by Willems, 

 and with weakened virus to inoculate in a region rich in connective tissue. 

 This, it is claimed, can be done safely with virus which has been kept six 

 weeks in a hermetically sealed tube (Pastenr), or with what has been 

 cultivated for a length of time in flasks in a special manner (Bruylants 

 and Verriest). Virus diluted with 50, 100, and 500 times its amount of 

 inert liquid still remained dangerous. (Vaudermies: Central Society 

 of Veterinary Medicine, Paris.) 



The danger of the propagation of the disease by inoculation is really 

 very slight. Yet he acknowledges the presence of the virulent micro- 

 coccus in the inoculation exudate, and advocates inoculation as a means 

 of procuring pure virus for further protective inoculation. 



To obviate the slight danger of lung infection through inoculation he 

 advocates the nse of attenuated virus {a la Pasteur, or a Ics Bruylants 

 et Verriest) and the intravenous injection of the virus pure or attenu- 

 ated. (It is to be noted that an absolute immunity is not claimed for 

 any method, nor an absolute protection againat the propagation of the dis- 

 ease by the inoculated ; the claim is that these may be reduced to a very 

 small figure. It follows that the protective inoculation is a measure of 

 repression, not extinction.! and to a case like ours, where a prompt stamp- 

 ing out is imperative, it is (piite inapplicable.) This is the more evident 

 from Degive's opinion that "all inoculated animals are to be regarded 

 as suspected of infectipn, and treated as such, and that after the com- 

 ])letion of the operation all virulent products should be thoroughly de- 

 stroyed or buried." 



To obviate losses from inoculation he i)articularly advises the use of 

 attenuated virus or intravenous injection, and to avoid the operation 

 during hot and rainy seasons. 



For the destruction of the poison it is necessary to attend to all fodder 

 (which has remained infecting for 3, 4, and even 9 months), all articles 

 about the stables, or suspected cattle, all other animals (not bovine) 

 that have cohabited with them, all places (buildings, &c.) where they 

 have been, all vehicles used for their conveyance or that of their prod- 

 ucts, and all persons that have come near them or the infected places. 

 The infected herd, the carcasses, and fresh products must receive, of 

 course, the lirst attention. Thorough destruction or disinfection of all 

 these is absolutely essential. 



As the discovery of iufection is the corner-stone of success, it must 

 be made obligatory on all owners and attendants on cattle, on all veter- 

 inarians and inspectors of abattoirs and meat markets, to promi)tly re- 

 port all cases of the disease, under a heavy penalty for disobedience and 

 for the owner a liberal indemnity for cattle and objects destroyed. 



At his visit the official veterinarian must note the animals sick and 



