INFECTIOUS DISEASES. 555 



case, too, ft)r ii few days the submuxillurv space may so swell a.s to 

 resemble the ecleinatt)iis, inflainetl <;l:iii(ls of sti iin<i:les, eiiuine variola, 

 or laryngitis. This condition is especially liable to be marked in an 

 acute outbreak of glanders in a drove of mules. 



Cases of chronic farcy and glanders, if not destroyed, may li\e in 

 a depraved condition until the animal dies from general emaciation 

 and anemia, but in the majority of cases, from some sudden exjjosure 

 to ct)ld, it develops an acute pneumonia or other simj)le inflammatory 

 trouble which starts the latent disease and tlie animal has aciito 

 glanders. 



In the ass, mule, and plethoric horses acute glanders usually termi- 

 nates by lobular j)neumonia. In other cases the general symptoms 

 may subside. The symptoms of pneumonia gradually disappear, tho 

 temperatuie lowers, the i)nlse becomes slowei', the ulcers heal, leaving 

 small, indurated cicatrices, and the animal may return to apparent 

 health, or may at least be able to do a small amount of work with but 

 a few symi^toms of the disease remaining in a chronic form. During 

 the attack of acute glanders the inllammation of tho nasal cavities 

 frequently spreads into the sinuses or air cells, which are found in the 

 forehead and in front of the eyes on either side of the face, and causes 

 abscesses of these cavities, which may remain as the only visible symj)- 

 tom of the disease. An animal which has recovered from a ease of 

 acute glandeis, like the animals which are affected by chronic gland- 

 ers and chronic farcy, is liable to be affected with emphysema of the 

 lungs (heaves), and to have a chronic cough. In this condition it 

 nuiy continue for a long period, serving as a dangerous source of con- 

 tagion, the more .so becau.se the slight <iuantity of discharge does not 

 serve as a warning to the owner or driver as profu.se discharge does 

 in the more acute cases. 



At the post-moilem examination of an aninud which has been de- 

 stroyed or has died of glanders we find evidences of the various 

 lesions which we have studied in the .symptoms. In addition to this, 

 we find nodules similar to those which we have seen on the exterior 

 throughout the various organs of the body. Nodules nuiy be found 

 in the liver, in the spleen, and in the kidneys. We may find inflam- 

 mation of the periosteum of the bones, and we have excessive altera- 

 tions in the nuirrow in the interior of the bones themselves. Both 

 the.se conditions during the life of the animal may have been the 

 cause of the lainenes.ses which were dillicult to diagnose. 



In one case which came under the observation of the writer, a lame 

 horse was destroyed and found to lune a huge abs<-ess of the bone of 

 the aim, with old nodules of the lungs. When an animal has died 

 innnediately after an attack of a primary, acute case of glandei-s, we 

 find siiu\ll V-.shape«l spots of acute pneumonia in the lungs. If the 

 animal has nuide an apparent lecovery from acute glander>, and in 



