viii A PATHOGENIC BACILLUS 69 



In specimens made of broth and Agar cultures : 

 The majority in length 1.6-2.4 A*" 



In specimens from gelatine cultures : 

 Length of the majority 0.8 /x. 



By comparing these figures with those given of 

 the bacilli in grouse disease it will be seen that 

 our malignant oedema bacilli are distinctly longer 

 than those of the grouse disease. 



Another difference is the distribution of the bacilli 

 in the animals (mice and guinea-pigs) infected : the 

 grouse bacillus is present in the blood and spleen 

 in greater abundance than our malignant oedema 

 bacillus ; the cedematous swelling in the guinea-pig 

 after inoculation with oedematous fluid or cultures 

 of our oedema bacillus is always more pronounced 

 than after inoculation with the cultures of the grouse 

 bacillus. Rabbits are susceptible to our malignant 

 oedema bacillus, but insusceptible to the grouse 

 bacillus. 



If guinea-pigs or rabbits are inoculated with a 

 drop of the oedema fluid, or with a good dose 

 of our malignant oedema bacillus, the animals are 

 found ill and quiet as early as 12 hours after inocula- 

 tion ; they are found dying or dead in from 20 to 36 

 hours with considerable oedema and haemorrhage in 

 the groin, on the abdomen, and chest. Sections made 

 through the skin, the subcutaneous and muscular 



