134 Preeipitina injected into Rabbits 



to act. Finally the traces of albumin demonstrated by means of 

 antisera disappeared, nevertheless egg-white persisted in the serum 

 of the immune rabbit. 



The behaviour of precipitins injected into normal animals has been 

 the subject of investigation by Obermayer and Pick (1902). They 

 injected anti-egg serum intraperitoneally into rabbits, and noted its 

 appearance after 15 minutes in the rabbits' circulation, the quantity 

 undergoing a rapid increase, a fact which could be observed by removing 

 samples of blood from the animals' ear veins at stated intervals. Control 

 experiments with subcutaneous injections showed that the precipitins 

 appeared much more slowly in the blood when this mode of administra- 

 tion was employed. The authors conclude that the rapid diffusibility of 

 these substances argues against their being of an albuminous nature. 



