THE PATHOGENIC HEMOSPORIDIA 289 



have come to the same conchision, that the drug acts directly upon the 

 parasite, kilhiig it with more or less distinct evidences of disintegra- 

 tion of the organism. INIarchiafava and Celli conclude that the treat- 

 ment is most effective during the period of sporulation and upon the 

 young stages of the organism, and practically without effect during 

 the period of pigment formation and full growth of the schizonts. 



19 



