27 



Smit found Pfeiffer's bacillus in all of the 24 cases of whooping- 

 cough examined in Utrecht in the spring and summer of 1903, 

 and in 7 out of 8 cases of whooping-cough in Amsterdam in the 

 spring of 1904. 



Davis (1) (Chicago 1906) found it in 56 out of 61 cases of 

 whooping-cough; also in measles (13 out of 22 cases), varicella (7 

 out of 11), bronchitis (5 out of 12), while it was only found in 

 3 out of 17 cases of „influenza". Lastly it was obtained from I be 

 throat of 2 out of 20 healthy persons. 



Woi.lstein (2) (New York 1909) found the bacillus in 10 out 

 of 20 cases of whooping-cough. 



With regard to the question of the occurrence of Pfeiffer's ba- 

 cillus in conjunctivitis L. Muller (1900) and zur Nedden (1903) 

 among others may be referred to. 



In the winter of 1904—05 „influenza" was rather wide- 

 spread over Europe and America. 



Besancon & de Jong (Paris) during this epidemic could only 

 occasionally find Pfeiffer's bacillus. From a review they give of 

 the results obtained in different countries it appears that it was 

 found in most places but was very inconstant. 



It was obtained relatively frequently by 



Jochmann (2) (Breslau), namely in 13 out of 36 cases in broncho- 

 pneumonia, usually in abundance. He states however he found 

 it considerably more extensively during an epidemic in Kiel in 1899. 

 Apropos of Wassermann's report of the epidemic in 1900 Jocn- 

 MANN remarks that in those cases where Pfeiffer's bacillus was 

 present it could usually be demonstrated for a long lime. 



Jochmann states that when Pfeiffer's bacillus is found in diph- 

 theria it has no effect on the course of the disease in some in- 

 stances, while in others it may cause bronchitis and broncho-pneu- 

 monia, but these cases do not however resemble influenza nor do 

 they differ clinically from the corresponding infections produced by 

 Streptococcus or Pneumococcus. 



Kretz (2) (Vienna 1905) reports a number of positive findings 

 of Pfeiffer's bacillus where there was a marked connection between 

 the quantity of bacilli and well-developed symptoms. 



STERNRERG (Vienna 1905) found Pfeiffer's bacillus in 13 out 

 of 70 cases which clinically might be suspected to be „ influenza", 

 while in the preceding winter he could only demonstrate it in 

 4 out of 56 samples of sputum. 



Klienererger (1) (Frankfurt a. M.) found Pfeiffer's bacillus 

 in 8 out of 27 „influenza" cases. He claimed that the inconstant 

 finding of the bacillus could not be attributed to defective technique, 

 since in that laboratory they had worked for several years with haemo- 

 globinophilic bacteria. 



