37 



Tytler, Janes, & Dobbin (also in about 90o/ of the cases). 



Williams (New Ydrk 1918) examined over 300 patients and 

 found Pfeiffer's bacillus in 80— 100o/ of the cases in the diffe- 

 rent groups. The earlier in the disease the examination was made, 

 the more often was Ffeiffer's bacillus found in large quantities in the 

 naso-pharynx. Cultivations from this place taken through the mouth, 

 yielded positive results more constantly than cultivations from other 

 parts of the mucous membrane. The next best result was from 

 the tonsils. t 



In a ,, Girl's Home" where there had been no influenza, Pfeif- 

 fer's bacillus was found in only 2 out of 34 girls and both of 

 these were kept apart on account of a slight „cold". In contrast 

 to this Pfeiffer's bacillus was present in 14 out of 39 persons in a 

 ^preventorium" where there had been influenza. 



Duval & Harris (New Orleans) in 1918—19 found the bacillus 

 in every one of 75 patients examined also in the lungs in 16 out 

 of 17 autopsies. 



Opie, Freeman, Blake, Small, & Rivers (Arkansas) exami- 

 ned 23 influenza patients for Pfeiffer's bacillus by several different me- 

 thods and found it in all, at least in one of the examinations, but 

 with no single method did they succeed in getting constant po- 

 sitive results. Injection of sputum into a mouse gave the most 

 positive results viz. 18, then came direct cultivation from the spu- 

 tum (14), from the throat (13), and from the nose (5). The examina- 

 tions were fairly evenly distributed over the period from the 1st. to the 

 6lh. day of the disease. 



Small & Stangl (Chicago) found Pfeiffer's bacillus during an 

 epidemic in Jan. and Feb. 1920, in 65 out of 67 influenza patients. 

 In non-influenza patients it was found in 9 out of 26 before the 

 epidemic, and in 21 out of 30 during the epidemic. 



As an indication that Pfeiffer's bacillus was also widely 

 distributed in influenza in other parts of the world than Europe 

 and North America, the following may be cited: 



Kraus & Kantor (Buenos Aires) found it in 36 out of 60 cases. 

 In 29 autopsies it was found in the spleen in 11, in the liver 

 in 5 and in the kidneys in 4 cases. 



Lister & Taylor found Pfeiffer's bacillus in 53 out of 56 post 

 mortem examinations on miners who had died from influenza in 

 the Transvaal and Johannesburg. 



Malone (1) (Calcutta) with suitable technique found Pfeiffer's 

 bacillus in the majority of cases in the sputum and in empyema 

 of the accessory sinuses. 



Okawara, Tanaka, Watanabe, Koyama, & Sato, in the pan- 

 demic which spread over Japan from Sept. to Nov. 1918, found 

 Pfeiffer's bacillus in 14 out of 46 samples of sputum and in 19 out 

 of 28 samples of nasal secretion. 



