40 



TYTLER, Janes, & Dobbin cultivated Pfeiffer's bacillus from Hie 

 heart blood in 2 out of 50 autopsies. 



DuJARRic DE LA Biviere cultivated Pfeiffer's bacillus from a 

 catheter specimen of urine in 10 influenza patients while it could 

 not be obtained* from the blood. This occurrence in the urine 

 is in agreement with the finding of Pfeiffer's bacillus in the kidneys 

 previously spoken of. 



Whether Orticoni & Barbie's strikingly frequent finding of 

 Pfeiffer's bacillus in the blood (in 38 out of 62 cases) is reliable, 

 is open to doubt. They stale firstly, to which no particular impor- 

 tance can be attributed, that the bacillus was a little larger than 

 the ordinary Pfeiffer's bacillus, and secondly that it grows .,difficilc- 

 ment" on ordinary media. But one of the essentials in the diagnosis of 

 Pfeiffer's bacillus is that in pure culture it practically never grows 

 on ordinary bloodfrce bouillon or agar. 



Concerning the occurrence of Pfeiffer's bacillus in ani- 

 mals I have only found one communication. 



Olsen (3) stales that in pneumonia in dogs that had died of 

 distemper, there were found „in grossen Massen hamoglobinophile 

 Stabchen, die sich mil den Qblichen Differenzierungsmelhoden (Kul- 

 tur, Agglutination, Komplementbindung) bisher in keiner Weise vom 

 Pfeifferschen Influenzabacillus unterschciden liessen".* This account 

 is however no good enough to convince one that it really was 

 Pfeiffer's bacillus and not the Bacillus haemoglobinophilus canis 

 (FRIEJ)BERGER) which is distinguished from Pfeiffer's bacillus by 

 some important characters, although Odaira found representatives 

 of the two organisms to be identical from a serological point of 

 view. Concerning „Bacillus seplicaemiae canis" (Paranhos) see p. 



There is no information about the occurrence of Pfeifler's 

 bacillus or other haemoglobinophilic bacteria „in Nature" apart 

 from the human or animal organism. 



The Occurrence of Pfeiffer's Bacillus in the Blood, 

 Meninges Etc. Virulence. 



Up to the present we have only discussed the occurrence 

 of Pfeiffer's bacillus in the blood and in those organs to 



* I have later had the opportunity of speaking with Dr. Olsen, 

 who staled that the bacilli exhibited the „symbiosis-phenomenon". 

 They must, then, probably be considered as Pfeiffer's bacilli. 



