76 



find the bacillus in pneumonia. Perhaps it is rather less frequent 

 here than in uncomplicated cases. The figures are too small 

 to permit of any definite conclusion however. 



The sputa also, which displayed the „classical a microsco- 

 pic picture with dense masses of Pfeiffer's bacilli from which 

 they could be cultivated almost in pure culture, are met with 

 in the different stages of the disease, both in complicated and 

 in uncomplicated cases. 



Furthermore, material from 41 autopsies on cases of 

 influenzal pneumonia from 5. XII. 1918—25. III. 1919 was exa- 

 mined. 



From each corpse cultivations were made as a rule from 

 2 or 3 different places in the affected lung, principally from 

 the peripheral portion of the pneumonic area and from places 

 where particularly fresh pneumonic lesions were present. In 

 some cases additional cultivations were made from the upper 

 air passages. 



Altogether, Pfeiffer's bacillus was found in 21 (51%) of 

 these 41 autopsies. 



In 7 cases I was able to express drops of pus from the small 

 bronchioles out on to the cut surface of the lung and I then made 

 cultivations from these drops as well as from the pneumonic lung 

 tissue. Pfeiffer's bacillus was cultivated from the drops of pus 

 in 2 cases, and from the lung tissue in 3. 



In 2 cases this microbe was found practically in pure culture 

 (without its being seen however in the microscopic preparation). 

 In cases where it was associated with other bacteria (Staphylo- 

 coccus, Streptococcus, Pneumococcus 5 sometimes also with other kinds) 

 it was always in the minority compared with the latter, at any 

 rate in the microscopic preparation. In the cultures colonies of 

 Pfeiffer's bacillus were present in some cases in about the same 

 numbers as the colonics of other bacteria. 



Out of 4 cases of catarrhal, membranous, or ulcerous inflam- 

 mation of the larynx and trachea Pfeiffer's bacillus was cultivated 

 twice and Staphylococcus twice. 



Pfeiffer's bacillus was found once in cultivations from 51 

 pleural exudates, some made during life and some post mortem'. 



The cidture plates (blood-agar, haemoglobin-agar) were inocu- 

 lated on the spot and then conveyed, — at a rather cool lempe- 



