81 



2. Whoopingscough. 



On the 19. Ill and 20. III. 1919 I collected the sputa of 

 12 children with typical whooping-cough (in Dr. Ad. Meyer's 

 clinic) and obtained Pfeiffer's bacillus from all of them', in 

 11 cases a luxuriant growth sometimes even in pure culture. 



How many of the children had influenza before admission 

 is not known, but they came from entirely different parts of 

 the town and so they could hardly have been all attacked. 

 Furthermore influenza did not prevail in the clinic during 

 these children's stay there. We cannot thus assume any direct 

 connection between the marked occurrence of Pfeiffer's bacillus 

 and influenza. 



On the 12. VII. 1919 the sputum of 5 children (in the same 

 clinic) was examined. Pfeiffer's bacillus was present in large 

 numbers in 2 of them. 



On. the 19. IX. 1919 an examination was made (at the Bleg- 

 dams-IIospital) of 21 children. Cultivations were made from 

 the sputum of 7 of these, with 5 findings of Pfeiffer's bacil- 

 lus. In 13, cultivations were made only from 1 the throat or 

 mouth, with 6 positive results. In one patient the throat cul- 

 ture gave a positive result, but the sputum a negative one. 

 Thus the microbe was found in 12 of the 21 patients. 



In many of the sputa it was present in considerable quanti- 

 ties; in other cases it was mpre scanty. 



With a few exceptions the children had coughed for 1—4 

 months. The large majority of cases were complicated with 

 bronchitis or broncho-pneumonia. 



In all cases an inoculation on Bordet's potato-glycerin- 

 blood-agar was made in addition to haernoglobin-agar, for the 

 isolation of the whooping-cough bacillus which was only found 

 in one case. This small result was however to be expected 

 in view of the late stages in the disease at which the examina- 

 tions were made. 



3. Measles. 



On the 9. I. 1920 inoculations from the throats of 31 

 measles patients were made at the Blegdamshospital. 



