52 PARASITES OF MAN 



myself that these immature trematodes from the nerves of the 

 cod-tribe can have no genetic relation with Bilharzia ; and I 

 think it due to Dr Maddox to say that I accept his conclusion 

 respecting them. In his paper (' Micros. Trans./ vol. xv, 1867, 

 p. 87) he offers strong proof that the so-called Distoma neuronaii 

 Monroii of the haddock (Morrhua aglefinus) is the juvenile 

 condition of Gasterostoma gracilescens of the angler (Lophius 

 piscatorius) . 



I am sorry to have to state that all my experiments proved 

 negative. I tried to induce the ciliated embryos to enter the 

 bodies of a variety of animals, such as Gammari, Dipterous 

 larvae, Entomostraca, Lymnaei, Paludinse, different species of 

 Planorbis, and other mollusks ; but neither in these, nor in 

 Sticklebacks, Roach, Gudgeon, or Carp, did they seem inclined 

 to take up their abode. 



The very peculiar and formidable helminthiasis produced by 

 this parasite has been thoroughly investigated by Griesinger 

 and Bilharz, and it has been fully described in the standard 

 works of Kiichenmeister and Leuckart. My own case from 

 Natal also supplied many interesting clinical facts which 

 were published in my ' Lectures on Helminthology/ quoted 

 below. The comparative prevalence of this disorder in Egypt 

 is well established. Symptomatically, its principal feature 

 consists- in a general disturbance of the uropoietic functions. 

 Diarrhoaa and haematuria occur in advanced stages of the com- 

 plaint, being also frequently associated with the so-called 

 Egyptian chlorosis, colicky pains, anaemia, and great prostra- 

 tion of the vital powers. The true source of the disorder, 

 however, is easily overlooked unless a careful microscopic 

 examination be made of the urine and other evacuations. If 

 blood be mixed with these, and there also be a large escape of 

 mucus, a minute inspection of the excreta will scarcely fail to 

 reveal the presence of the characteristic ova of Bilharzia. 

 Besides the increase of mucus secretion, there may even be 

 an escape of purulent matter, showing that the disorder has 

 far advanced. The patient's constitution eventually becomes 

 undermined ; pneumonia often sets in, and death finally ensues. 

 On making post-mortem examinations the following pathological 

 facts come to light. In cases where the disease has not advanced 

 very far, minute patches of blood-extravasation present them- 

 selves at the mucous surface of the bladder, but in more 

 strongly pronounced cases the patches are larger or even 



