184 PARASITES OF MAN 



hgematuria. He also afterwards found them in a man whose urine 

 was slightly chylous, but not haematic. In all cases these 

 sexually -immature nematodes were alive. In September, 1872, 

 Dr A. Corre furnished a careful description of similar worms 

 found by Dr Crevaux in a haemato-chylurous patient at Guade- 

 loupe. Dr Crevaux frequently examined the blood of this 

 patient but found no haematozoa. In like manner in Brazil, 

 Dr J. Silva Lima sought in vain for worms in the blood of no 

 less than five patients, all of whom suffered from haematuria, 

 and whose urine contained numerous nematoid worms. 



Towards the close of the year 1872 the biological world was 

 startled by the announcement of the discovery of minute Filariaa 

 in human blood. Dr T. R. Lewis had found microscopic worms 

 in the blood, and also in the urine, of persons suffering from 

 chyluria. The worms could be obtained from day to day by 

 simply pricking any portion of the body with a finely pointed 

 needle. To this haematozoon Lewis gave the trinomial term 

 Filaria sanguinis hominis, which thus fitly distinguished it from 

 the Filaria papillosa hamatica canis domestici described by 

 Grube and Delafond. Dr Lewis found the average size of the 

 parasite to be y^" in length by 53^5" in breadth. He observed 

 that while it exists in the blood the body is enclosed in a 

 delicate transparent tunic or cyst. The worm was never absent 

 from urine in chyluria. In a case in which there was a milky 

 discharge from the eyes the worms were also detected. In one 

 case Lewis calculated that 140,000 Filarias were present in the 

 blood a number certainly not relatively large seeing that MM. 

 Grube and Delafond estimated the verminiferous blood of their 

 several dogs to contain numbers varying from 11,000 to 224,000. 

 Lewis also found Filarise in the kidneys and supra-renal 

 capsules of a woman who died of chyluria. It did not appear 

 probable that the worms underwent further development in the 

 huinan body. On this point Lewis remarks : " Not only may 

 those haematozoa found in man live for a period of more than 

 three years, but there is no evidence that they have any 

 tendency to develop beyond a certain stage as long as they 

 remain in the circulation." Dr Lewis judged that the form of 

 chyluria associated with this condition of the blood was local 

 and intimately related with a tropical climate. The milky 

 condition of the urine comes on suddenly, not only at first, but 

 on succeeding occasions also. It is frequently accompanied by 

 more or less distinctly marked symptoms of various other 



