178 MAN AN ADAPTIVE MECHANISM 



A. B. 



Section of normal human cerebellum Section of human cerebellum after 

 (after accidental death). death from carcinoma. 



FIG. 36. EFFECT OF CARCINOMA ON THE BRAIN-CELLS OF A HUMAN 



BEING. 



All the Purkinje cells in focus in B show loss of chromatic material. In 

 some (indicated by arrows) the evidence of deterioration is so great as to 

 leave but the faintest outline of the cell. 



(From photomicrographs, X 310.) 



of change was from a first stage of hyperchromatism to 

 chromatolysis and the physical breakdown of some cells. 

 Whether the stimulating agent was physical exertion, 

 prolonged emotional excitation, severe injury, the injec- 

 tion of strychnin, the toxins of disease, or the persistent 

 maintenance of consciousness under normal conditions, 



