THE KINETIC SYSTEM 



181 



spleen or kidneys. Adrenin itself is more alkaline than 

 normal blood. The H-ion concentration of the blood 

 in the adrenal vein as compared with that of the blood 

 in other parts of the circulation is therefore an index 

 of the amount of adrenin in the blood. We found 

 an increased H-ion concentration in intense emotion ; 



J-cc W*" 

 S-KA.'n AffelT 



A. B. 



FIG. 38. TRACING SHOWING EFFECT OF SKATOL ON THE ADRENAL OUT- 

 PUT OF A DOG. (Cannon Test.) 



The first tracing A was made by the contractions of intestinal muscle 

 in blood from a normal dog. The second tracing B shows the partial 

 inhibition of the contractions produced by the substitution of blood after 

 the injection of skatol, evidencing the presence in the blood of an increased 

 amount of adrenin. 



in exertion, in traumatic shock ; in asphyxia ; in deep 

 hemorrhage ; and during the inauguration of the phe- 

 nomena of death from any other cause. 



The biologic test for adrenin was negative i.e., 

 functional activity of the adrenals was apparently not 

 excited in every instance in which the above activations 



