350 MAN --AN ADAPTIVE MECHANISM 



Granting this, we can understand clearly why acidosis 

 is so frequently seen in severe cases of Graves' disease 

 and why acidosis results from violent fever. We can 

 understand the occurrence of albumin and casts in the 



A. B. 



Section of normal human cerebellum. Section of human cerebellum after 

 (After accidental death.) death from acute acidosi-. 



FIG. 85. EFFECT OF ACUTE ACIDOSIS ON THE BRAIN-CELLS OF A HU- 

 MAN BEING. 



In B note the complete disintegration of the Purkinje cells of which but 

 faintest traces remain. (See arrows.) 



(From photomicrographs, X 310.) 



urine as a result of exertion or emotion and in Graves' 

 disease. 



The H-ion Factor in Graves' Disease 



Having noted that the symptoms of Graves' disease 

 resemble closely those of extreme exertion, of intense 



