ACUTE INTOXICATION RABBITS. 



25 



March 18: 9 a. m., found dead, but still warm. Autopsy: Lungs studded with 

 small grayish white nodules, adhesions to costal pleura; probably lesions of cpccidiosis; 

 livt -r studded with coccidiosis nodules. Hemorrhages at point of inoculation. 

 Rabbit, 551. Gray, female. Weight, January 6, 1,650 gram*. Diet, oats; fed 20 cc of 

 X5 per cent alcohol daily from January 26-31. 



January 31: Weight, 1,450 grams; 10.20 a. m., temperature 101.6; 10.45, a. m., 

 temperature 101.6; received 7 cc 2 per cent caffein suocutaneously into back; 11.15 

 a. m., convulsions of short duration; raised himself on posterior legs, anterior legs 

 wide apart; 4.10 p. m., looked normal, not hypersensitive; 4.30 p. m., condition 

 seemed to be good. 



February 1 : 9 a. m. , found dead, was alive at 5.30 p. m. of previous day. Autopsy: 

 Lesions found involved thoracic cavity mainly; lungs were hepatized and a nbro 

 plastic exudate caused them to adhere to costal pleura; liver engorged and appeared 

 fatty; no marked lesions affecting digestive tract, a slight catarrh of stomacn being 

 the only noticeable feature; kidneys and spleen normal. 



TABLE 1. Subcutaneous injections of caffein rabbits. 

 SERIES A. 



SERIES B, GROUP I. 



SERIES B, GROUP II. 



SERIES C. 



