140 THE PHYSIOLOGY OF REPRODUCTION 



discharged and partially degenerating in situ. Amongst those who 

 have adopted this view are Nagel, 1 who investigated the human 

 corpus luteum ; Clark, 2 who contributed an account of the formation 

 of the corpus luteum in the sow and in the human subject ; Doering, 3 

 who also worked upon the sow, and claimed to have confirmed Clark's 

 account ; and Biihler, 4 Wendeler, 5 and Stockel,* 5 who have examined 

 and described developing human corpora lutea. Moreover, His, 7 

 Kolliker, 8 and Paladino 9 have reiterated their adherence to von 

 Baer's hypothesis since the publication of Sobotta's work. 



It is remarkable, however, that none of the supporters of this 

 hypothesis appear to have examined the growing corpus luteum in 



FIG. 40. Late stage in formation of corpus luteum of mouse. (From 

 Sobotta.) Thecal ingrowths are numerous. The cavity of the 

 follicle is not yet filled in. 



all its stages of development, while in the case of several of the 

 accounts it is not clear whether the structures described were not in 



1 Nagel, "Die Weiblichen Geschlechtsorgane," Bardeleben's Handbuch der 

 Anatomic ties Menscken, vol. vii., Jena, 1896. " Uber neuere Arbeiten auf dem 

 Gebiete der Anatomic der weiblichen Geschlechtsorgane," Merkel and Bonnet's 

 Ergebnisse d. Anat. u. Entwick., vol. viii., 1899. 



2 Clark, "Ursprung, Wachstum, und Ende des Corpus Luteum," Arch. f. 

 Anat. ^t. Phys., Anat. Abth., 1898 ; Johns Hopkins Hospital Reports, vol. vii., 

 1899. 



3 Doering, " Beitrag zur Streitfrage iiber die Bildung des Corpus Luteum," 

 Anat. Anz., vol. xvi., 1899. 



4 Biihler, " Entwickelungsstadien Menschlichen Corpora Lutea," Verhand. 

 d. Anat. tiesell., in Pavia, 1900. 



5 Wendeler, Martin's Die Krankheiten der Eierstocke und Nebeneierstocke. 



6 Stockel, " Ueber die Cystiche Degeneration der Ovarien bei Blasenmole," 

 Sep. Abdnwk am der Festschrift fiir Fritsch. 



7 His, Discussion, Verhand. d. Anat. Resell., in Tubingen, 1899. 



8 Kolliker, "Ueber Corpora Lutea Atretica bei Saugethieren," Verhand. d. 

 Anat. Gesell., in Kiel, 1898. 



9 Paladino, "Per la Dibuttata Questione sulla Esenza del Corpo Luteo," 

 Anat. Am., vol. xviii., 1900. 



