YELLOW FEVER 253 



Asia. In Europe its ravages have been restricted to 

 Spain, to which country it has several times been 

 introduced by means of ships coming from the West 

 Indies. 



In the United States several severe epidemics oc- 

 curred in the city of Philadelphia during the latter 

 part of the eighteenth century (1793, 1797, 1798), 

 but since that time the ravages of the disease have, 

 for the most part, been confined to more southern 

 localities. 



During the first sixty years of the past century it 

 prevailed almost annually in one or more of the 

 Southern seaports of the United States and not 

 infrequently it extended its ravages to the interior 

 towns in one or more of the Southern States. So 

 frequently did it prevail during the summer months 

 in New Orleans and Charleston that the permanent 

 residents of those cities commonly regarded it as a 

 disease of the climate and a necessary evil which 

 it was folly to attempt to combat by quarantine 

 restrictions. 



In the great epidemic of 1853, yellow fever pre- 

 vailed extensively in the States of Florida, Alabama, 

 Louisiana, Mississippi, Arkansas, and Texas. The 

 epidemic of 1867 was limited to the States of Louisi- 

 ana and Texas. Those States again suffered severely 

 in 1873, and the States of Florida, Alabama, and 



