YELLOW FEVER 255 



The demonstration that yellow fever is propagated 

 from man to man by mosquitoes of the genus Ste- 

 gomyia was made by a board of medical officers of 

 the United States army, which was appointed upon 

 the recommendation of the present writer, and which 

 prosecuted its researches in Cuba during the years 

 1 900 and 1 90 1 . This board consisted of Major Walter 

 Reed, Surgeon U. S. A. ; Dr. James Carroll, Con- 

 tract Surgeon U. S. A. ; Dr. A. Agramonte, Contract 

 Surgeon U. S. A. ; and Dr. Jesse W. Lazear, Con- 

 tract Surgeon U. S. A. 



In a " Preliminary Note," read at the meeting of 

 the American Public Health Association, October 22, 

 1 900, the board gave a report of three cases of yellow 

 fever which they believed to be the direct result of 

 mosquito inoculations. Two of these were members 

 of the board, viz., Dr. Jesse W. Lazear and Dr. 

 James Carroll, who voluntarily submitted themselves 

 to the experiment. Dr. Carroll suffered a severe at- 

 tack of the disease and recovered, but Dr. Lazear 

 fell a victim to his enthusiasm in the cause of science 

 and humanity. His death occurred on September 

 25th, after an illness of six days' duration. About 

 the same time nine other individuals who volunteered 

 for the experiment were bitten by infected mosqui- 

 toes i. e., by mosquitoes which had previously been 

 allowed to fill themselves with blood from yellow 



