HYDROPHOBIA 287 



these cases the animal which inflicted the bite was 

 proved to be rabid by experimental inoculations 

 made in other animals with an emulsion of the 

 brain or spinal cord. This is now generally recog- 

 nised as a conclusive demonstration that an animal, 

 or man, from whom such virulent material has been 

 obtained, was a victim of rabies. 



Perdrix (1890) in an analysis of the results obtained 

 at the Pasteur Institute in Paris calls attention to the 

 fact that the mortality among those treated has dimin- 

 ished each year and ascribes this to improvements 

 in the method employed. In the cases with severe 

 wounds upon the head and face larger doses of the 

 virulent material are used at more frequent intervals. 

 Perdrix gives the following statistics with reference 

 to the location of the bite as influencing the results 

 of treatment. 



Bitten upon the head, 684; died, 12 = 1.75 <f> 

 Bitten upon the hands, 4396; died, 9 = 0.2 % 

 Bitten upon the limbs, 2839; died, 5 = 0.17 # 



Recently the statistics of the Pasteur Institute in 

 Paris for a period of sixteen years (1886 to 1901) 

 have been published. During this period 112 deaths 

 occurred among 25,986 persons inoculated a mor- 

 tality of 0.43 %. It is not claimed that all of the 

 inoculated had been bitten by rabid animals. In 

 many cases it is impossible to ascertain whether the 



