246 BIOLOGY OF SPECIALIZED GROUPS 



Bacterium leprae (Leprosy). 

 Treponema pallidum (Syphilis). 

 Spirochaeta obermeieri (Relapsing fever). 

 Amoebi coli (Amoebic dysentery) . 

 Plasmodium malariae (Malaria). 



There are other bacteria, as, for example, the M. gonor- 

 rhceae, which fulfill all but one or two postulates. In this case 

 M. gonorrhoea will not produce the disease when inoculated 

 into animals. There are still other bacteria which have been 

 proved to be the etiological agents in diseases which do not 

 comply with all the laws. The constant association of defi- 

 nite microorganisms with diseases showing the same symptom- 

 atology has led to these organisms being regarded as specific. 



Effects of Pathogenic Bacteria on the Body. The fol- 

 lowing tabular outline is given by Muir and Ritchie and por- 

 trays in a very general way the action of the pathogenic bac- 

 teria on the animal body. 



A. Tissue Changes. 



(1) Local changes. In region of the bacteria. 

 Position (a) At primary lesion. 



(b) At secondary foci. 

 Character (a) Tissue reactions. 



(b) Degeneration, acute or chronic. 



(2) Changes produced at a distance from the bacteria 



directly by the absorption of toxins. 

 (a) In special tissues 



