202 MICROBIOLOGY 



Pathogenesis. It is fatal to rabbits when inoculated in- 

 travenously or into the abdominal cavity with 0.5 cc. of a 

 bouillon culture in from 2 to 3 days. In one case fowls inocu- 

 lated intravenously with a small dose (0.1 to 0.3 cc.) died 

 within 48 hours. Magnusson 4 has described a new disease 

 of fowls in Europe due to a streptococcus. He has identified 

 it as apoplectiform septicemia. 



STREPTOCOCCUS OF INFECTIOUS PNEUMONIA OF HORSES. 



Place in nature. In 1887, Schiitz x described microorgan- 

 isms which he isolated from the tissues of horses suffering from 

 infectious pneumonia or Brustseuche. He described them as 

 small oval bacteria which appeared as diplococci, and in the 

 cultures as short chains. They stained with methylene blue 

 and other basic aniline dyes, but were not stained by the Gram 

 method. A number of investigators described organisms some- 

 what similar to that found by Schiitz. Hell 2 was unable to 

 differentiate the bacteria of Brustseuche from the pyogenic 

 streptococci. He believed that the organism described by 

 Schiitz was the specific cause of Brustseuche. The earlier lit- 

 erature on this organism does not give its cultural characters 

 sufficiently to differentiate it from other streptococci found in 

 lesions in the horse. 



In 1897, the writer isolated from the lungs of two of three 

 fatal cases of this disease which occurred in an outbreak in 

 Ithaca a streptococcus in pure culture which possessed mor- 

 phological and cultural characters of the Streptococcus pyo- 

 genes* Pfeiler, 3 after studying 24 cases of Brustseuche, con- 

 cludes that the diplo-streptococcus of Schiitz is the cause of 

 the disease. While there are strong indications that the organ- 



4 Magnusson. Centralbl. f. Bakt., Bd. LVI (1910) p. 411. 

 Schiitz. Virchow's Archiv, Vol. CVII (1887) p. 356. 



2 Hell. Quoted by Friedberger u. Frohner. 



* Evidence of the cocco-bacillus of Lignieres either in cultures or 

 in stained sections of the tissues was not found. 



3 Pfeiler. Zeit. f. Infektionskrankheiten u. Hyg. der Haustiere, 

 Bd. VIII (1910) p. 155. 



