278 MICROBIOLOGY 



bad effects were discovered. The same results were obtained 

 when larger quantities were injected. No effect is produced 

 by feeding large quantities of the culture to adults. 



Half grown guinea pigs when injected subcutaneously 

 with the culture die in from twenty-four to forty-eight hours. 

 The essential lesion is a large edematous area beneath the skin 

 of the abdomen. The organisms are recovered in pure culture 

 from the internal organs. A rabbit weighing 1,660 grams 

 injected subcutaneously with 3 cc. of a forty-eight hour 

 bouillon culture died in seven days. The most pronounced 

 lesions were enlargement, softening and congestion of the 

 heart. The bacterium was recovered from all the internal 

 organs in pure culture. 



BACTERIUM RHUSIOPATHIAE (KITT) MIGULA. 



Synonyms. Bacillus of swine erysipelas Loeffler l 

 Bacillus rkusiopathiae suis Kitt c ; Bacterium erysipelatus suis, 

 Migula. 3 



Place in nature. This organism is the cause of a disease 

 in swine known in England as swine erysipelas, in Germany 

 as Eotlauf and in France as rouget. Jensen 4 describes five 

 varieties of Eotlauf due to this organism that were previously 

 considered as different diseases. Eotlauf or swine erysipelas 

 is not known to exist in America. In 1894 Dr. Theobald 

 Smith 5 isolated and described an organism from rabbits that 

 were inoculated with tissues from pigs sent to him from Min- 

 nesota which resembled Bacterium rliusiopathiae but which 

 was not positively identified. This organism was discovered by 

 Pasteur and Thuillier 6 and later studied in pure culture and 



1 Loeffler. Arbeiten aus dem Kaiserl. Gesundheitsamt, Bd. I 

 (1886) p. 46. 



2 Kitt. Bakterienkunde u. pathologische Mikroskopie, 1893, p. 284. 

 1 LOG. cit. 



4 Jensen. Deutsche Zeitschr. f. Thiermed., Bd. XVIII (1892) p. 



278. 



'Smith, Annual Report B. A. I., U. S. Dept. Agric., 1895-1896, 

 Pasteur et Thuillier. Compt. rendu de 1'Acad. des Sci., Vol. 



XCV (1882) p. 1187. 



