356 MICROBIOLOGY 



dominate, and it is in this animal that the disease is presented 

 in its most typical form. The symptoms generally noted are 

 diarrhoea, albuminuria, fever, and in the most chronic cases, 

 cachexia and paralysis, which Charrin considers of a perfectly 

 characteristic type, and in which the hind quarters are the 

 ones most frequently involved. The paralysis is essentially 

 spastic in nature. At autopsy the animals show congestion of 

 the mucous membrane of the intestine and usually small 

 hemorrhages in the various viscera, but more constantly in 

 the intestinal walls. Schaefer, 5 who carried on his experiments 

 with the dog, arrived at results not unlike those obtained by 

 Charrin. Cadeac, 6 shortly after the publication of Charrin 's 



results, reported a case 



f s P ntaneous pyocya- 

 neus infection in a dog. 

 Since this there has 

 ^ een an a ^undance of 

 experimental evidence 

 which is essentially con- 

 firmatory of the conclu- 

 sions of Charrin, Led- 

 Fig. 74.' Pseudomonas pyocyaneus. derhose and Schaefer. 

 much enlarged. It has been found to be 



widely distributed i n 



nature, occurring on the skin, in feces of animals and in puru- 

 lent discharges. 



Morphology. Slender rods from 0.3 to 1 /x broad and 

 from 2 to 6 /x long; frequently united in pairs or in chains 

 of four to six elements; occasionally growing out into long 

 filaments and twisted spirals. It is actively motile, a single 

 flagellum being attached to one end. It does not form spores. 

 Staining. It stains with the ordinary aniline colors ; does 

 not stain with Gram's solution. 



5 Schaefer. Inaug. Diss., Berlin, 1891. 



6 Cadeac. Comp. rendu de la Soc. de Biol., n. s. Vol. II (1890) 

 p. 41. 



