72 Mr. P. Koorevaar on the 



in the fat a green granular mass ; above it is flabby and 

 cedematous. 



With a view to making sure whether these spinal lavvse 

 ■were the larvje of Ilypoderma, T inserted them under the skin 

 of another animal, in order that they might there become 

 adult and in order from them, if possible, to breed Hypo- 

 derma bovis. 



I selected as subject of experiment a small dog, which 

 since the beginning of January liad been supplied witii food 

 infected with Echinococcus veterinorum. On February 3rd 



1 introduced, under aseptic precautions, through an opening 



2 centimetres wide, beneath the skin in the left lumb'\r region 

 eleven Sj'inal ffi'.v/r«/5-larva3 taken from a calf. The wound 

 •was closed and healed quickly, the state of the dog remained 

 normal, and nothing was seen of the eleven larvae inserted. 



Eight days later in the same manner fifteen larvce were 

 introduced under the skin of the right side ; scarcely an hour 

 later one of my colleagues and I reopened the wound, and saw 

 to our astonii^hinent that all the larvae witii the exception of 

 one had disappeared. Two days afterwards I observed a 

 larva lying under the skin on the costal wall, 8 centimetres 

 away from the wound ; its rounded oblong form was dis- 

 tinctly visible through the tliin skin of the dogj one could 

 feel it roll under the finger. On the third day it had crawled 

 forward as far as the spinous processes, and on the fourth it 

 had disappeared. 



The dog remained normal ; fourteen days after the first 

 insertion tiiere was still nothing to be seen under the skin. 

 What had become of the twenty-six larvae in the dog? 

 To settle the point I decided to open the animal. 

 The autopsy was interesting. 



On removing the skin five still living larva? were found in 

 the subcutis — one on the left costal wall, one in front of the 

 Bhoulder, one on the right thigh, one on the skull, and tlio 

 fifth larva on the point of the jaw. In the subcutis and in 

 the underlying muscles no traces of their wanderings were 

 observable; but certain oedematous spots were found in the 

 subcutis and tlie muscles. 



On opening the abdomen some bloody matter exuded. 

 Six larvEe were found between the folds of the intestine, and 

 therefore free in the peritoneal cavity. 



I found, further, five Idl-vje in the fat of the spleen, kidneys, 

 omentum, inguinal canal, and the retro-peritoneal tissue; the 

 removal of the kidneys disclosed three more larvge upon the 

 psoas muscles. 



In the pleural cavities no larvje were found lying free ; still 

 five larvje were met with, three of which were in the wall of 

 the oesophagus and two in the peritracheal tissue. 



