Larval Stage 0/ Hypodevma bovis. 73 



The discovery in the spinal canal was very remarkable ; 

 on exposing the cord it was found that two larvte were 

 ensconced in the fat between tlie dura mater spinalis and the 

 ];eriosteum : the fat around the place was somewhat softer 

 and injected w ith blood. 



All the twenty-six larvae introduced were found, and for 

 the most part alive. 



They had wandered far in a relatively short time — eight to 

 fourteen days after they had been introduced under the skin. 



In spite of careful examination no traces or tracks of the 

 course followed by the larvae could be found. 



Certain small oedematous patches were indeed present in 

 the subcutis and between the muscles, and some bloody 

 humour was found in the abdominal cavity. 



On February 17th I introduced in the same manner twenty 

 spinal (Estrus-\B.\V2S. under the skin of an eighteen-months-old 

 he-goat. So far as 1 am aware, the larvae of Ili/poderma bovis 

 are not found in the goat. 



On February 29th I found in the he-goat five subcutaneous 

 swellings, each with a central opening, from which there 

 exuded a dirty white fluid. I propose to allow these larvte to 

 mature. 



I fed two young dogs simultaneously with spinal (Estrus- 

 larvfe, introduced into the pharynx by means of a spatula. 

 The dogs were killed after two and four days respectively. 

 On autopsy I have been unable to find a single larva outside 

 the alimentary tract or remains of the larvse in the stomach 

 or intestine. 



I introduced ten larvse directly into the oesophagus of a 

 rabbit by means of a rubber tube. For three days I examined 

 the faeces; but neither in them nor in the rabbit, which I 

 afterwards killed, could I find any trace of the injected larv«. 



As it appeared from the autopsy of the dog, the larvae 

 introduced under the skin wandered about into various places 

 agreeing with those in which they are found in cattle. This 

 discovery, in connexion with the negative result produced by 

 the introduction of the larvEe per os, causes me to incline to 

 the opinion that the young larvge of IJypoderma bovis at first 

 pass beneath the skin, and from thence betake themselves to 

 the spinal canal and other places, to return later into the 

 subcutis and there undergo further development under the 

 well-known conditions. 



I hope later on to publish a communication as to the dis- 

 covery of the further development of the spinal larv£e beneath 

 the skin of the he-goat. 



March, 1806. 



