14 



Itagaki 



In four other experiments in the cat, portions of the circular muscle 

 of the small intestine were employed; three of these showed distinct 

 diminution of tone ; in the fourth no clear effect was observable. 



Bladder of Rabbit. — Three experiments were made with strips 

 of the rabbit's bladder, the mucous membrane having been shaved off. 

 In all three cases diminution of tone was observed. 



The Iris of the Frog. — The eyes of a frog which had just been 

 killed were enucleated and immersed, the one in Locke solution and 

 the other in Locke extract of corpus luteum, the diameters of the pupils 

 being carefully measured from time to time. The following table is a 

 re cord of two experiments : — 



Table II. 

 A. 



It will be observed that there is no perceptible effect produced by corpus 

 luteum. 



Effects on Blood-pressure and on Volume of Kidney. 



A number of experiments were made to determine whether intravenous 

 injection of the extract produces any definite effects upon blood-pressure 

 and kidney volume, and also, in some experiments, on the flow of urine ; 

 in lactating animals the flow of milk was observed. Blood-pressure was 

 taken from the carotid artery. 



No. 



1 

 2 

 3 



Date. 



12.12.15 

 29.12.15 

 30.12.15 



Table I XL — Rabbit. 



Dose. 



5% 5 c.c. 





Blood-pressure. 



Fall 



No change 



Kidney 

 volume. 



Increase 



Remarks. 



No change iu 

 pulse rate. 



