Action of Kxtracts of (Jvary on Plain Muscle 31 



tone. One of tliese experiments was made with a uterus wliich had been 

 kept forty-eitjht hours in an ice-cliest. 



Action on tlie Small Intestine. 



The experiments upon the small intestine were made partly witii 

 portions of the whole tul)e, partly with strips of the lontjitudinal coat. Of 

 the experiments on the whole tube, three were performed with rabbit's 



Fig. 5. — Effect of extract of hilum ovarii on the intestine (wliole tube) of the rabbit. Notice the 

 increase of tone with gradual diminution of amplitude of the rhythmic movements. The 

 first mark on the lowest line indicates the aj>plication of hilum extract, the second its 

 replacement by simjile Locke. 



intestine and two with the intestine of a kitten. All these, without 

 exception, showed an increase of tone (fig. 5). The strength of the extract 

 employed was from 3 per cent, to 10 per cent. Eight experiments were 

 performed with longitudinal strips of the intestine of the rabbit, the 

 strength of the extract used being from 2 per cent, to 10 per cent. AH 

 showed relaxation of tone, the "pendulum movements" being arrested 

 (fig. 6) by the stronger solutions (above 5 per cent.), but not by the 

 weaker (from 2 per cent, to 5 per cent.). 



