34 



Itagaki 



Action on Blood-pressnre. 

 Injection of from 5-7 c.c. of a 5 per cent, to 15 per cent, extract causes 

 a marked fall of blood-pressure in the cat (fig. 9). 



p„; 9 —Eifect on blood-pit-ssure of cat of an intravenous injection of 7 c.c. of a mixture of IT. j.arts 



liquor folliculi and 85 of Locke, 

 a, l)lood-pressure tracing ; b, time in 10-sec. intervals ; c, sitfiial. 



Extracts of Whole Ovary. 

 For this purpose, small ovaries were selected containing neither large 

 corpora lutea nor large Graafian follicles. After being weighed, they 

 were minced, boiled with Locke solution, filtered, and the filtrate made 

 up to the original volume by the addition of distilled water. 



Action on Uterus of Rat. 



In four experiments this extract in every case produced diminution in 

 extent or complete inhibition of the rhythmic movements (fig. 10). The 

 strength of the extracts employed varied from 5 per cent, to 10 per cent. 



