Action of certain (llninl Kxtrncts and Drugs upon rterus of Rat 41 



tjot's into persistent contraction; lliis, Imwivfr, ])ri*scntly ^ivcs way lu a 

 rhythmic contraction, at tii-st of small amplitucii', hut ^nadually increasing; 

 in extent (tii;. 2). Sometimes the increase of tone is maintained for a 



Fig. 2. — Effect on cornu of rat-uterus suspended in Locke's solution of the addition of 

 extract of j)osterior lobe of ])ituitary of ox. Time in minutes. 



considerable time. The contraction caused by the extract of pituitary 

 is somewhat similar to that of extract of corpus luteum. 



Extract of the anterior lobe of the pituitary body does not, so far as 

 my observations go, produce any effect. 



A DR EX A UN. 



A large number of experiments have been made by previous workers 

 regarding the action of adrenalin upon the uterus. Most have been upon 

 the cat, rabbit, and guinea-pig, but some upon the human uterus, and one 

 series upon the rat's uterus. The general results can be sunnned up in 

 the following table, which is based on one given by Gunn (6): — 



