Kfiect of Tliyroid-Feediii^' on the Supraivuiils 



53 



According to Carlson, Kook.s. aii<i .M Kie (5) tin- l<jxic cHVcta of 

 thyroid-feediii;:: arc i)artly iiscril)iil)le to excess of protein, hut only so 

 when the dose is excessive. This is certainly not the case with anumnts 

 of from 0-2 to O.") ;cr'n- fnsh thyroid daily. In the second series of rats 

 an equivalent amount of raw ox Hesii was i^iven daily to the control 

 animals (Table III.). It does not appear to have caused any departure from 

 the normal. 



Tablk III. 



-Second Skuiks. Xormaf. Rats of the .same Aar. kei» (*x BrkaI) 

 AND Milk +0-2 Gum. Fbksh Ux Flksu daily. 



The Adrenalin Content of the Sl'pkarenal.s. 



The amount of adrenalin in the suprarenals of the normal rat shows 

 considerable variation. As a (general rule it increases with the atje and 

 weight of the animal. The larger the suprarenals the more adrenalin do 

 they contain, but exceptions are not infrequent. In the first series of 

 normal rats (Table II.) the average adrenalin content is 00()5 n)g., the 

 lowest amount beincr 0-081 mg. in the second animal, and the highest 

 0-110 mg. in the last and largest rat. The amount of adrenalin per 

 100 grm. body- weight is more constant, and averages 0-084 mg. for the 

 thirteen rats. The percentage amount in the suprarenals averages 0-224. 



In the second series of normal animals the average adrenalin content is 

 0-048 mg., which expres.sed in mg. per 100 grm. body-weight is 0-083 mg.. 

 a figure which agrees very well with the average 0-034 mg. of the first 

 series. The percentage in the suprarenals in this series is lower, and 

 averages O'lOG. 



The administration of thyroid increases the adrenalin content. In the 

 first series of rats (Table II.) the adrenalin content of the suprarenals 

 averages 0-088 mg. as the result of feeding with thyroid. The lowest 

 content of the series is 0-057 mg. in the third animal, and the highest 

 0-138 mg. in the thirteenth rat. The amount of adrenalin per 100 grm. 



