IIG 



Blair Bell 



examined histologically the vesicles were seen to be enormously distended 

 with colloid (fig. 41). 



Imitation Tumours in the Neighbourhood of the Pituitary. 



These experiments were three in number, but dog No. 26 was killed 

 on recovering from the anaesthetic, as she seemed to be in pain. The 

 details of the experiments are shown in Table IX. The procedure was the 

 same in all cases : the region of the sella turcica was exposed by the usual 

 method, and the tumour was placed in proximity to the pituitary. 



Table IX. — Imitation Tumour in Sella Tuucica. 



The artificial tumour was made of wax mixed with barium oxychloride, 

 and was sterilised by heat. This substance when softened was easily 

 placed in situ after being moulded into the shape of a bun (figs. 42 

 and 43). The X-ray photographs were taken during life some weeks after 

 operation. It will be observed that in neither case does the artificial 

 tumour occupy the site of the sella turcica centrally, but there is no doubt 

 from the post-mortem examination that in both cases the pituitaries were 

 somewhat displaced (fig. 44), and in one case (No. 20) the pars anterior 

 contained a large cyst (fig. 45). 



In one animal (No. 20) there was very considerable emaciation, 

 with slight glycosuria. With regard to the general condition of this 

 animal (fig. 46), it will be noticed that it presents the appearances 

 described by Crowe, Gushing and Homans (1910 (6)), and stated to be 

 due to a specific " cachexia hypophyseopriva." It has already been 

 mentioned that in my experiments no evidence was obtained of any such 



