Studies on the Endocrine Glnnds 



333 



in the number ol oxypliil cells. All the cells of the crhmd are swollen, and 

 their cytoplasm has a loose open appearance ; the cell-nuclei are little altered. 

 The pars posterior also has an open reticular appearance, as if there were 

 an accumulation of Huid within it. 



8. Feedinij with addition of adrenalin causes great enlargement of certain 

 cells in the pars anterior : these seem to be the oxyphils 



9. Feeding with sodium iodide or with potassium iodide causes an 

 increase of chromaphobe cells with a concurrent reduction of chromaphil 

 cells, both oxyphils and basiphils being involved. 



Microscopic Appearances of the Pituitary of the Dog. 

 The pars anterior is compact in structure. Oxyphil cells are in large 

 number, especially near the periphery : in fact, most of the cells of this part 



^<? 





Fig. 11. — Section of ]>ituitary body of normal dog (male). Microphotograph ; magnified 75 

 diameters, Hfematoxylm-eosin {>re})aration. 



The pars anterior contains numerous oxyphil cells which in the photograph appear dark. 

 Numerous vesicles, either round or elongated, occur in tlie pars intermedia, which also con- 

 tains an extension of the intraglaniiular cleft. The blood-vessels in the pars anterior are 

 large and sinus-like, giving a peculiar mottled appearance to the section. 



a, pars anterior; b, pars intermedia, with cleft between them ; c, pars nervosa. 



are oxyphil. Thev contain distinct granules, staining with eosin. Their 

 nuclei are spheroidal, and measure about oz-i. The chromatin-granules 



