Studies on the Endocrine Glands 



335 



Effects of PMitial Thyroidectomy in Dot;. 



This operation was performed by Professor Schiifer upon a young male 

 fox-terrier weighing ()400 grm. Care was taken to leave the parathyroids 

 whilst removing as much of the thyroid tissue as possible, about two- 

 thirds of the total thyroid tissue being removed ; the portion of thyroid 

 removed was, after fixation, submitted to section, and the series of sections 









Fig. 1-3. — Section of {lituitaiy of a partially thyroidectomised dog (male) showing,' a large cyst 

 containing colloid and several smaller ones in the substance of the pars anterior, and a 

 considerable number of colloid-containing cysts in the pars intermedia. Microphotograpli ; 

 magnified 75 diameters. Hsematoxylin-eosin preparation. 



The colloid witiiin the cysts is stained faintly pink by haematoxylin-eosin. The sinusoid 

 capillaries give a mottled appearance to the pars anterior. Notice an exten.sion of the 

 intraglandular cleft into tlie pars intermedia. 



a, pars anterior ; b, para intermedia ; c, pars nervosa. 



investigated. They showed no parathyroid. The wound had completely 

 healed a week after the operation. The animal was fed throughout with 

 dog-biscuits, except for a fortnight in December, when it was given horse- 

 flesh, with the view of determining whether the parathyroids had been 

 completely removed ; but in spite of the flesh diet no symptoms of tetany 

 appeared. After the operation the animal's weight increased, and continued 

 to do so until it was killed — nine weeks after the operation, — when its 

 weight was found to be 7450 grm. 



VOL. XL, NO.S. 3 AND 4. — 1917. 22 



